Program Manager – Product Management

Remote – South Africa


Drive complex programs. Enable better outcomes.
At Signant Health, we are modernizing clinical trials through innovative technology that simplifies data capture, accelerates delivery, and improves the experience for patients and sponsors. We’re currently hiring a Senior Program Manager to lead large-scale, cross-functional programs that align product, engineering, and business operations to deliver real impact.


What You’ll Do

As a Senior Program Manager, you will play a critical role in delivering strategic initiatives across our global teams. You’ll ensure programs are delivered on time, on scope, and with measurable outcomes—empowering innovation in how we deliver evidence generation solutions.


• Lead end-to-end delivery of complex programs across Product, Engineering, and Operations

• Develop program plans, track dependencies, and manage risks to delivery

• Collaborate with senior stakeholders to align priorities and resolve challenges

• Provide regular updates on program health and performance to executive sponsors

• Contribute to program management best practices and mentor teams on delivery excellence

What You Bring

We’re looking for a highly organized and results-oriented professional who can navigate complexity, build strong relationships, and keep teams focused on outcomes.

• 8+ years of program management experience in software development or product delivery

• Proven success in managing multi-functional initiatives with global teams

• Deep understanding of the software development lifecycle (Agile, Scrum, etc.)

• Strong communication and stakeholder engagement skills

• Bachelor’s degree in Computer Science, Business, or related discipline

• Familiarity with tools such as Jira, Smartsheet, Confluence, or similar

About Signant Health
We are the evidence generation company. At Signant Health, we help life sciences companies securely capture and manage clinical trial data to bring new treatments to market faster. With a global team of experts and purpose-built technology, we’re enabling smarter trials for better outcomes.


At Signant Health, accepting difference isn’t enough—we celebrate it, we support it, and we nurture it for the benefit of our team members, our clients and our community. Signant Health is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or veteran status.